Mobile Phone Weight-Loss Application For Women Starting A Meal Replacement Programme
We developed and tested a mobile phone application (app) to support individuals embarking on a partial meal replacement programme (MRP). Overweight or obese women were randomly allocated to one of two study groups. The intervention group received an MRP Support app. The control group received a static app based on the information available with the MRP. A total of 58 adult women (Support n = 28; Control n = 30) participated in the 8-week trial. Their BMI was 26-43 kg/m2. Usage data suggested that the intervention group were more engaged with using the app throughout the study period. Mixed modelling revealed that the difference in weight loss between the intervention and control groups (estimated mean, EM = 3.2% and 2.2% respectively) was not significant (P = 0.08). Objective data suggested that users of the Support app were more engaged than those using the control app. A total of 1098 prompts (54%) asking people in the intervention group to enter their meals were completed prior to the evening prompt. Women in the intervention group reported a greater increase in positive affect (i.e. mood) than those in the control group (EM = 0.48 and -0.01, respectively) (P = 0.012). At Week 8, those in the control group reported a greater decrease in the effort they were willing to put into staying on the diet than those who received the Support app (EM = -2.8 and -1.4, respectively) (P = 0.024). The Support app could be a useful adjunct to existing MRPs for psychological outcomes.
Weight-Loss Surgery May Affect Fat-Related Genes
Weight-loss surgery changes the levels of genes involved in burning and storing fat, a new study says.
The findings may help lead to the development of new drugs that mimic this weight-loss-associated control of gene regulation, said the authors of the study published online April 11 in the journal Cell Reports.
"We provide evidence that in severely obese people, the levels of specific genes that control how fat is burned and stored in the body are changed to reflect poor metabolic health," senior author Juleen Zierath, a professor with the Karolinska Institute in Sweden, said in a journal news release.
"After [weight-loss] surgery, the levels of these genes are restored to a healthy state, which mirrors weight loss and coincides with overall improvement in metabolism," Zierath explained.
Weight-loss surgery -- also called bariatric surgery -- can help obese people lose large amounts of weight in a short time. The surgery also leads to early remission of type 2 diabetes in many patients.
Some Slightly Obese May Gain From Weight-Loss Surgery, Guidelines Say
TUESDAY, April 16 (HealthDay News) -- Even people who are slightly obese could be candidates for weight-loss surgery under new guidelines released by three U.S. medical groups.
The groups recommended that eligibility for weight-loss (bariatric) surgery be expanded to include mildly to moderately obese people with diabetes or metabolic syndrome, which is a group of conditions that put people at increased risk for heart disease and diabetes.
Under the new rules, eligible patients would have a body-mass index (BMI) of 30 to 34.9. BMI is a measurement of body fat based on height and weight.
There is not enough current evidence, however, to recommend weight-loss surgery for blood sugar control alone, fat lowering alone or heart disease risk reduction alone, independent of BMI criteria, the guidelines said.
The American Society for Metabolic and Bariatric Surgery, the American Association of Clinical Endocrinologists and the Obesity Society issued the guidelines. They were published in the latest editions of the journals Surgery for Obesity and Related Diseases, Endocrine Practice and Obesity.
Among the 74 recommendations in the guidelines:
Sleeve gastrectomy is reclassified as a proven method of weight-loss surgery, rather than an experimental one.Women should avoid pregnancy before weight-loss surgery and for 12 to 18 months after surgery.A team approach to patient care around the time of surgery is "mandatory with special attention to nutritional and metabolic issues."Other recommendations cover topics such as patient screening and selection, deciding on the best type of weight-loss surgery, and criteria for readmitting patients to the hospital after they've had weight-loss surgery.
The previous guidelines were issued in 2008.
"Bariatric or metabolic surgery is among the most studied surgical interventions in medicine and this ever-increasing mountain of evidence continues to show that these procedures are the most successful and durable treatment for obesity and several related diseases," Dr. Daniel Jones, a member of the 12-person panel that developed the guidelines, said in a news release from the American Society for Metabolic and Bariatric Surgery.
"However, we've gleaned important new insights, cautions and best practices based on the thousands of studies that were published in medical journals in just the last four years alone and these are reflected in the new guidelines," said Jones, a professor of surgery at Harvard Medical School.
-- Robert Preidt
Copyright © 2013 HealthDay. All rights reserved. SOURCE: American Society for Metabolic and Bariatric Surgery, news release, April 5, 2013